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KMID : 0370220100540020122
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Yakhak Hoeji
2010 Volume.54 No. 2 p.122 ~ p.125
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Study on Activities of the Essential Oil from Elsholtzia ciliata against Some Antibiotic-Susceptible and -Resistant Strains of Pathogenic Bacteria
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Shin Seung-Won
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Abstract
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The essential oil fraction was extracted from the aerial parts of the plant by steam distillation method and its composition was analyzed by GC-MS (gas chromatography-mass spectrometry) which led to the identification of 43 compounds. Dehydroelsholtzia ketone (56.81%) and elsholtzia ketone (30.05%) were identified as the predominant components of this oil. The antibacterial activities of the essential oil fraction were assessed by micro-dilution tests against antibioticsusceptible and -resistant strains of Streptococcus pneumoniae, Staphylococcus aureus, Salmonella enteritidis, and S. typhimurium. The oil inhibited most of the tested strains significantly resulting MICs (minimum inhibiting concentrations) between 2 mg/ml and >16 mg/ml. In most cases of this study Streptococcus pneumoniae and Staphylococcus aureus showed higher sensitivity to this oil than Salmonella strains.
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KEYWORD
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essential oil, Elsholtzia ciliata, antibiotic-resistance, elsholtzia ketone, dehydroelsholtzia ketone, Streptococcus pneumoniae, Staphylococcus aureus, Salmonella enteritidis, S. typhimurium
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